Clinical review 84: Thyroid autonomy: mechanism and clinical effects.
نویسندگان
چکیده
منابع مشابه
CLINICAL REVIEW Thyroid eye disease
Thyroid eye disease is a relatively rare condition, with an incidenceof 2.9 to16.0 casesper100 000population per year. The disease mainly affects women. Many patients experience distressing symptoms, and a few develop sight threatening complications. Patients are often young or middle aged and at the peak of their career. Most patients are very aware of their altered appearance. Sight loss canb...
متن کاملClinical review 133: Progress in understanding the etiology of thyroid autonomy.
The etiology of thyroid autonomy and autonomously functioning thyroid nodules has been reviewed, with emphasis on histological (1, 2), molecular (3), and clinical aspects (4) as well as transgenic animal experiments that model thyroid autonomy (5). Somatic TSH receptor (TSHR) mutations have been discovered as the most prevalent molecular event in the etiology of autonomously functioning thyroid...
متن کاملClinical review: Thyroid dysfunction and effects on coagulation and fibrinolysis: a systematic review.
CONTEXT Various changes in the coagulation-fibrinolytic system have been described in patients with an excess or deficiency of thyroid hormones. The purpose of this systematic review is to summarize the effects of hyperthyroidism and hypothyroidism on these systems. EVIDENCE ACQUISITION All published case-control or interventional cohort studies that evaluated the effects of hyperthyroidism a...
متن کاملThyroid disruption: mechanism and clinical implications in human health.
Exposure to specific environmental toxins, including polychlorinated biphenyls, dioxins, phthalates, polybrominated diphenyl ethers (PBDEs), and other halogenated organochlorines, has been shown to interfere with the production, transportation, and metabolism of thyroid hormones by a variety of mechanisms. A broad range of chemicals, with structural similarity to thyroid hormone, have been show...
متن کاملmicroRNAs and thyroid cancer: biological and clinical significance (Review).
Despite recent advances in the management of thyroid cancer, the survival rate of this tumor may still be improved. Therefore, the identification of biological and molecular features of indolent and aggressive disease would be critical to define clinically useful predictors of high-risk lesions. microRNAs (miRNAs) are small RNA molecules with regu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 1996
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.81.12.8954013